Fluconazole Tablet
Fluconazole Tablet
Fluconazole is an antifungal medicine that is used to treat infections caused by fungus, which can invade any part of the body including the mouth, throat, esophagus, lungs, bladder, genital area, and the blood.
Fluconazole is also used to prevent fungal infection in people who have a weak immune system caused by cancer treatment, bone marrow transplant, or diseases such as AIDS.
Fluconazole is also used to treat a certain type of meningitis in people with HIV or AIDS.
Fluconazole, the first of a new subclass of synthetic triazole antifungal agents, is available as tablets for oral administration.
[toggle title=”What is Fluconazole Tablet?” state=”close”]Fluconazole is a prescription medicine used to treat vaginal yeast infections caused by a yeast called Candida. Fluconazole tablet helps stop too much yeast from growing in the vagina so the yeast infection goes away.
Fluconazole tablet is different from other treatments for vaginal yeast infections because it is a tablet taken by mouth.
Fluconazole tablet is also used for other conditions. However, this leaflet is only about using fluconazole tablets for vaginal yeast infections.
For information about using fluconazole tablets for other reasons, ask your healthcare provider. See the section of this leaflet for information about vaginal yeast infections.[/toggle]
[toggle title=”What is a vaginal yeast infection?” state=”close”]It is normal for a certain amount of yeast to be found in the vagina.
Sometimes too much yeast starts to grow in the vagina and this can cause a yeast infection. Vaginal yeast infections are common. About three out of every four adult women will have at least one vaginal yeast infection during their life.
Some medicines and medical conditions can increase your chance of getting a yeast infection. If you are pregnant, have diabetes, use birth control pills, or take antibiotics you may get yeast infections more often than other women.
Personal hygiene and certain types of clothing may increase your chances of getting a yeast infection.
Ask your healthcare provider for tips on what you can do to help prevent vaginal yeast infections.
If you get a vaginal yeast infection, you may have any of the following symptoms: itching a burning feeling when you urinate redness soreness A thick white vaginal discharge that looks like cottage cheese[/toggle]
[toggle title=”Why you have been prescribed this medicine?” state=”close”]You have been prescribed this medicine if you have any of the following: Infections, caused by Candidas, including generalized candidosis, including candidemia, disseminated candidosis and other forms of invasive candidal infections (candidal infection of endocardium, eye, respiratory and urinary tract); mucous membrane candidiasis, including oral cavity, throat and esophagus; non-invasive bronchopulmonary candidal infections; candiduria; mucocutaneous and chronic atrophic candidiasis of tunica mucosa of mouth (caused by dental prosthesis wearing); genital candidiasis, vaginal candidiasis (acute or recurrent ), prophylaxis of vaginal candidiasis recurrence (in occurrence frequency of 3 or more times per year), and also of candidal balanitis; cryptococcal meningitis and infections of other localisations; dermatomycosis, including tinea pedis, tinea cruris, tinea unguium (onychomycosis), and also pityriasis versicolor; deep endemic mycosis, including coccidioidomycosis, paracoccidioidomycosis, sporotrichosis and histoplasmosis; fungal infections prophylaxis (cryptococcosis, oropharyngeal candidiasis) in patients, who receive cytostatic or radiation therapy, in patients with AIDS.[/toggle]
[toggle title=”When you should consult your doctor?” state=”close”]You should consult your doctor if you experience any of the following: Central and peripheral nervous system: headache, dizziness, convulsion, change of taste. Cardio-vascular system: QT-interval lengthening, paroxysmal ventricular tachycardia of the “pirouette” type.
Gastrointestinal tract: stomach ache, diarrhoea, dyspepsia, nausea, vomiting. Liver and bile-excreting system: often – toxic hepatic impairment, including single cases of fatal outcome, increase of levels of alkaline phosphatise, bilirubin, alanine aminotransferase (ALT) and aspartate aminotransferase (AST); sometimes – hepatic incompetence, hepatitis, hepatocellular necrosis, jaundice. Laboratory data: leucopenia, including neutropenia and agranulocytosis, thrombocytopenia, hypercholesterolemia, hypertriglyceridemia and hypokaliemia.
Immune system: anaphylaxis, including angioneurotic oedema, face oedema and skin itch, urticaria. Skin and its appendixes: alopecia, exfoliative skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrosis[/toggle]
[toggle title=”What to do if you miss a dose?” state=”close”]If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Otherwise take it as soon as you remember and then go back to taking it as you would normally.[/toggle]
[toggle title=”Things you MUST NOT DO while on this medicine?” state=”close”]AIDS patients are more susceptible to severe skin reactions upon usage of a lot of many drugs. If skin rash, which may be associated with Fluconazole usage, appears in patients who are on the treatment of superficial fungal infection, it is necessary to contraindicate the preparation.
If skin rash appears in patients with invasive/systemic fungal infections, it is necessary to observe the patients’ states and stop Fluconazole usage in a case of polymorphic erythema. In a case of successful treatment of chronic nail infection by Fluconazole it is sometimes observed a change of nail shape.
Drug interactions:
Patients who concurrently use other drugs must consult a doctor before the treatment start. Flutuff intensifies anticoagulants action, therefore in concurrent usage with cumarin anticoagulants it is necessary a precise control of prothrombin time.
In oral Midazolame the usage of Fluconazole can cause significant increasing of Midazolame concentration and psychomotor action appearance. If patient, who receive Fluconazole treatment, need benzodiazepine administration the dose of benzodiazepine should be reduced and patient must be on precise examination.
In concurrent usage of Fluconazole and Cisapride it was reported untoward cardiac reaction, including paroxysmal ventricular tachycardia of the “pirouette” type. Cisapride is contraindicated in patients, who receive Fluconazole. Fluconazole increases Cyclosporine concentration in their concurrent usage.
During Fluconazole treatment it is recommended to control concentration of Cyclosporine in blood. Multiuse of hydrochlorthiazide increases Fluconazole concentration in plasma approximately on 40%, but it is not necessary to change the dosage regimen of Fluconazole in patients who concurrently use diuretics.
Fluconazole does not influence on efficacy of combined oral contraceptives. Concurrent usage of Fluconazole and Fenitoin may be accompanied by Fenitoin concentration increase up to significant clinical level. If there is need of concurrent usage of both preparations then it should be a control of Fenitoin level and its adjustment for providing of therapeutic concentration in plasma.
Rifabutin level in blood serum is increased as a result of Fluconazole and Rifabutin interaction. In concurrent usage of Fluconazole and Rifabutin it was reported about uveitis cases. In concurrent usage of Fluconazole and Rifampicin Fluconazole dosage should be increased. In concurrent usage with per oral sulfonylurea drugs (chlorpromide, glybenclamide, glipizide and tolbutamide) Flutuff prolonges their half-excretion period.
Fluconazole and oral sulfonylurea drugs can be concurrently used in patients with insular diabetes, but it is necessary to take into account possible hypoglikemia development. Fluconazole intensifies Tacrolimus concentration in plasma. In concurrent usage of Fluconazole and Tacrolimus there were reported about cases of nephrotoxicity increasing. Terfenadine is contraindicated in patients who receive Fluconazole During Fluconazole treatment of patients, who receive high doses of Theophylline or who have an increased risk of Theophylline toxic actions, it is necessary to control appearance of symptoms of Theophylline overdosage, because Fluconazole decreases an average clearance speed of Theophylline from plasma. Zidovudine concentration in blood is increased in case of concurrent usage with Fluconazole.
Usage of Fluconazole in patients, who concurrently receive astemizole or others drugs, which are metabolized by cytochrome system P450, can be accompanied by increased concentrations of these drugs in blood serum. Fluconazole used simultaneously with meal, cimetidine and antacids does not change its absorption properties.[/toggle]
[toggle title=”What to do if you accidentally take too much (overdose) of the medicine?” state=”close”]
Symptoms: hallucinations and paranoiac behavior.
Treatment: Treatment is symptomatic (including gastric lavage and supporting therapy). Fluconazole is mainly excreted with urine, therefore forced diuresis can accelerate the preparation excretion. Dialysis during 3 hours decreases the concentration of the preparation in plasma by approximately on 50%.[/toggle]
[toggle title=”Is it safe in pregnancy and breast-feeding?” state=”close”]Tell your doctor immediately if you become pregnant while taking this medication. For safety of any drug during pregnancy or breastfeeding – please consult your doctor.[/toggle]
[toggle title=”Do not take fluconazole tablets if you.” state=”close”]take the following medicines:
- Quinidine
- Erythromycin
- Pimozide
are allergic to fluconazole, the active ingredient in fluconazole tablets, or any of the ingredients in fluconazole tablets. See the end of this Patient Information leaflet for a complete list of ingredients in fluconazole tablets.[/toggle]
[toggle title=”Before you take fluconazole tablets, tell your healthcare provider about all of your medical conditions, if you:” state=”close”]
- Have liver problems
- Have kidney problems
- Have heart problems including heart arrythmias have hypokalemia (low potassium)
- Are pregnant or plan to become pregnant. Tell your healthcare provider right away if you become pregnant while taking fluconazole tablets. You and your healthcare provider will decide if fluconazole tablets is right for you. If you may become pregnant you should use a birth-control (contraceptive) method while taking fluconazole tablets and for 1 week after your final dose.
are breastfeeding or plan to breastfeed. Fluconazole can pass into your breastmilk. Talk to your healthcare provider about the best way to feed your baby while you are taking fluconazole tablets.[/toggle]
[toggle title=”Storage Conditions?” state=”close”]Keep it out of reach of children, in a dry, dark place at temperature below 25 °C.[/toggle]
[toggle title=”Indications and dosage.” state=”close”]INDICATIONS: Infections, caused by Candidas, including generalized candidosis, including candidemia, disseminated candidosis and other forms of invasive candidal infections (candidal infection of endocardium, eye, respiratory and urinary tract); mucous membrane candidiasis, including oral cavity, throat and esophagus; non-invasive bronchopulmonary candidal infections; candiduria; mucocutaneous and chronic atrophic candidiasis of tunica mucosa of mouth (caused by dental prosthesis wearing); genital candidiasis , vaginal candidiasis (acute or recurrent ), prophylaxis of vaginal candidiasis recurrence (in occurrence frequency of 3 or more times per year), and also of candidal balanitis; cryptococcal meningitis and infections of other localisations; dermatomycosis, including tinea pedis, tinea cruris, tinea unguium (onychomycosis), and also pityriasis versicolor; deep endemic mycosis, including coccidioidomycosis, paracoccidioidomycosis, sporotrichosis and histoplasmosis; fungal infections prophylaxis (cryptococcosis, oropharyngeal candidiasis) in patients, who receive cytostatic or radiation therapy, in patients with AIDS. DOSAGE: Tablets for oral use.
The daily dosage depends on character and severity of fungal infection. The treatment of infections, which require repeated usage of the preparation, must be continued until clinic-laboratory effect reaching (decay of fungal infection). In candidemia, disseminated candidosis and other invasive candidosis the usual dose is 400 mg during the first day, then – 200 mg per day.
The daily dose can be increased up to 400 mg per day if there is a need. For adults in oropharyngeal candidiasis it is usually administered 50-100 mg of Fluconazole 1 time per day during 7-14 days. In patients with acute depressed immunity the treatment is prolonged if it is necessary. In atrophic candidiasis of tunica mucosa of mouth caused by dental prosthesis wearing the preparation is administered in 50 mg dose 1 time per day during 14 days concurrently with local antiseptic drugs for dental prosthesis treatment.
In other mucous membrane candidiasis (except generalized candidosis), for example esophagitis, non-invasive bronchopulmonary candidal infections; candiduria, cutis and mucous membrane candidiasis an effective dose is usually 50-100 mg in the treatment duration of 14-30 days. For prophylaxis of oropharyngeal candidiasis recurrence in patients with AIDS after the course of primary therapy by Fluconazole it is administered 150 mg 1 time per week. In vaginal candidiasis Fluconazole is used in 150 mg single dose per oral. For reduction of disease recurrence rate the preparation is used in 150 mg dose 1 time per month. The therapy duration is determined individually (from 4 to 12 months). In some cases usage frequency is increased. In balanitis, caused by Candida fungis, Fluconazole is administered per oral in 150 mg single dose.
For candidiasis prophylaxis the recommended dose is 50-400 mg 1 time per day depending on the degree of risk of fungal infection development. In presence of high risk of generalized infection, for example in patients with foreseen marked and long-term neutropenia, the recommended dose is 400 mg 1 time per day. Fluconazole is administered before several days to foreseen neutropenia occurrence; after increased number of neutrophilic granulocytes over 1000 in 1 mm3 the treatment is prolonged for 7 days more.
In cryptococcal meningitis and cryptococcal infections of other localisations it is usually administered 400 mg in the 1st day, and the treatment is continued in 200-400 mg dose 1 time per day. The treatment duration in cryptococcal meningitis is usually not less than 6-8 weeks. For prophylaxis of cryptococcal meningitis recurrence in patients with AIDS (after the end of the course of primary treatment) the therapy by Fluconazole in 200 mg dose per day can be prolonged.
In dermatomycosis, including tinea pedis, tinea cruris and in candidal infections the recommended dose is 150 mg 1 time per week or 50 mg 1 time per day. The therapy duration as usual is 2–4 weeks, but in mycisis of legs it may be necessary more long-term treatment (up to 6 weeks). In pityriasis versicolor the recommended dose is 300 mg 1 time per week during 2 weeks; some patients need the 3rd dose of Fluconazole 300 mg, whereas in some cases it is enough a single dose of 300-400 mg of the preparation.
Alternative treatment scheme is the preparation usage of 50 mg 1 time per day during 2 to 4 weeks. In onychomycosis (tinea unguium) the recommended dose is 150 mg 1 time per week. The treatment should be continued until change of affected nail on health one. For repeated fingernail and toenail growth it is usually necessary 3-6 and 6-12 months correspondingly, but growth rate may be varied within wide diapason in different people and in dependence on age. In deep endemic mycosis it may be necessary long-term (up to 2 years) administration of the preparation in 200-400 mg dose per day. The therapy duration is determined individually; it is usually 11-24 months in coccidioidomycosis, 2-17 months in paracoccidioidomycosis, 1-16 months in sporotrichosis and 3-17 months in histoplasmosis.
For the treatment of elderly patients in absence of kidney insufficiency symptoms the preparation is used in usual dose. For patients (including children) with kidney dysfunctions in multiuse of the preparation it is necessary to use a loading dose that is from 50 to 400 mg. The daily dose is determined by the table (depending on indexes) after loading dose usage. At the change from intravenous infusion to oral usage or contra verse it is not necessary to change the daily dose.
For children less than 7 years old Fluconazole is administered by the doctor’s recommendation. The daily dose for children does not exceed the dose for adults. In mucous membrane candidiasis the recommended dose of Fluconazole for children is 3 mg/kg. In the first day it may be used a loading dose of 6 mg/kg for faster reaching of stable balanced concentration.
For the treatment of generalized candidosis and cryptococcal infections the dose of Fluconazole for children is 6-12 mg/kg per day depending on the disease severity.
For fungal infection prophylaxis in patients with depressed immunity in which the risk of infection development is related to neutropenia that is a result of cytostatic chemical or radiation therapy, the preparation is administered 3-12 mg/kg/day depending on severity and keeping period of induced neutropenia. The duration of the treatment by Fluconazole for children depends on results of mycological examination and clinical presentation. It is determined individually.[/toggle]
[toggle title=”Side effects and drug interactions.” state=”close”]
ADVERSE REACTIONS: Central and peripheral nervous system: headache, dizziness, convulsion, change of taste. Cardio-vascular system: QT-interval lengthening, paroxysmal ventricular tachycardia of the “pirouette” type. Gastrointestinal tract: stomach ache, diarrhoea, dyspepsia, nausea, vomiting.
Liver and bile-excreting system: often – toxic hepatic impairment, including single cases of fatal outcome, increase of levels of alkaline phosphatise, bilirubin, alanine aminotransferase (ALT) and aspartate aminotransferase (AST); sometimes – hepatic incompetence, hepatitis, hepatocellular necrosis, jaundice.
Laboratory data: leucopenia, including neutropenia and agranulocytosis, thrombocytopenia, hypercholesterolemia, hypertriglyceridemia and hypokaliemia. Immune system: anaphylaxis, including angioneurotic oedema, face oedema and skin itch, urticaria. Skin and its appendixes: alopecia, exfoliative skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrosis.
Drug interactions:
Patients who concurrently use other drugs must consult a doctor before the treatment start. Flutuff intensifies anticoagulants action, therefore in concurrent usage with cumarin anticoagulants it is necessary a precise control of prothrombin time. In oral Midazolame the usage of Fluconazole can cause significant increasing of Midazolame concentration and psychomotor action appearance.
If patient, who receive Fluconazole treatment, need benzodiazepine administration the dose of benzodiazepine should be reduced and patient must be on precise examination. In concurrent usage of Fluconazole and Cisapride it was reported untoward cardiac reaction, including paroxysmal ventricular tachycardia of the “pirouette” type. Cisapride is contraindicated in patients, who receive Fluconazole. Fluconazole increases Cyclosporine concentration in their concurrent usage.
During Fluconazole treatment it is recommended to control concentration of Cyclosporine in blood. Multiuse of hydrochlorthiazide increases Fluconazole concentration in plasma approximately on 40%, but it is not necessary to change the dosage regimen of Fluconazole in patients who concurrently use diuretics. Flutuff does not influence on efficacy of combined oral contraceptives. Concurrent usage of Fluconazole and Fenitoin may be accompanied by Fenitoin concentration increase up to significant clinical level.
If there is need of concurrent usage of both preparations then it should be a control of Fenitoin level and its adjustment for providing of therapeutic concentration in plasma. Rifabutin level in blood serum is increased as a result of Fluconazole and Rifabutin interaction. In concurrent usage of Fluconazole and Rifabutin it was reported about uveitis cases. In concurrent usage of Fluconazole and Rifampicin Fluconazole dosage should be increased. In concurrent usage with per oral sulfonylurea drugs (chlorpromide, glybenclamide, glipizide and tolbutamide) Fluconazole prolonges their half-excretion period. Fluconazole and oral sulfonylurea drugs can be concurrently used in patients with insular diabetes, but it is necessary to take into account possible hypoglikemia development. Flutuff intensifies Tacrolimus concentration in plasma. In concurrent usage of Fluconazole and Tacrolimus there were reported about cases of nephrotoxicity increasing. Terfenadine is contraindicated in patients who receive Fluconazole.
During Fluconazole treatment of patients, who receive high doses of Theophylline or who have an increased risk of Theophylline toxic actions, it is necessary to control appearance of symptoms of Theophylline overdosage, because Fluconazole decreases an average clearance speed of Theophylline from plasma. Zidovudine concentration in blood is increased in case of concurrent usage with Fluconazole.
Usage of Fluconazole in patients, who concurrently receive astemizole or others drugs, which are metabolized by cytochrome system P450, can be accompanied by increased concentrations of these drugs in blood serum. Flutuff used simultaneously with meal, cimetidine and antacids does not change its absorption properties.[/toggle]
[toggle title=”Warnings and precautions.” state=”close”]AIDS patients are more susceptible to severe skin reactions upon usage of a lot of many drugs. If skin rash, which may be associated with Fluconazole usage, appears in patients who are on the treatment of superficial fungal infection, it is necessary to contraindicate the preparation. If skin rash appears in patients with invasive/systemic fungal infections, it is necessary to observe the patients’ states and stop Fluconazole usage in a case of polymorphic erythema. In a case of successful treatment of chronic nail infection by Fluconazole it is sometimes observed a change of nail shape.[/toggle]
[toggle title=”Overdosage and Contraindications.” state=”close”]Overdose: Symptoms: hallucinations and paranoiac behavior. Treatment: treatment is symptomatic (including gastric lavage and supporting therapy). Fluconazole is mainly excreted with urine, therefore forced diuresis can accelerate the preparation excretion. Dialysis during 3 hours decreases the concentration of the preparation in plasma approximately on 50%. CONTRAINDICATIONS: Flutuff should not be administered in individual hypersensitivity to Fluconazole or other agents similar to azole substance by chemical structure. Concurrent usage of Terfenadine is contraindicated in patients who use Flutuff. Cisapride is contraindicated in patients who receive Flutuff. Children age less than 7 years old. Lactation and pregnancy periods.[/toggle]
[toggle title=”Clinical pharmacology.” state=”close”]
PHARMACOLOGICAL PROPERTIES:
Pharmacodynamics: Flutuff is an antifungal agent of triazole substances. Fluconazole has an intensive antifungal action and specifically blocks fungal sterol synthesis. It has a specific action against fungal enzymes, which are depended on cytochrome P450. It is active against different Candida spp. (including visceral candidiasis), Cryptococcus neoformans (including intracranial infections), Microsporum spp. and Trichophytum spp. Fluconazole is also active against endemic mycosis: Blastomyces dermatitidis, Coccidioides immitis (including intracranial infections), Hystoplasma capsulatum. Pharmacokinetics: After per oral usage it is well absorbed in gastrointestinal tract, general bioaviability exceeds 90%. Meal does not influence on Fluconazole absorption. Maximal concentration in plasma is reached in 0.5–1.5 hours after intake. The period of half-excretion of Fluconazole from plasma is 30 hours, that allows to use it 1 time per day during the treatment course and provides the therapeutic effect in vaginal candidiasis after a single use of the preparation. The concentration of active substance in plasma is proportionate to the used dose. 11–12% of Fluconazole binds with plasma proteins. In 90% of patients the stable concentration of Fluconazole is reached on 4–5 days of everyday single usage. This effect is reached to 2nd day of the treatment after a loading dose (twice a day) in the first day of the treatment. Fluconazole well penetrates in fluids of the organism. Its concentrations in spittle and sputum are equivalent to the concentrations in plasma. The concentration of Fluconazole in spinal fluid is reached 80% from its concentration in plasma. The concentrations in epidermis, derma and sweat are reached the levels, which exceed plasma’s ones. It is excreted mainly with urine, and approximately 80% of it is excreted in unchanged form. Fluconazole clearance is directly proportional to creatinine clearance. PHARMACEUTICAL CHARACTERISTICS: General physic-chemical properties: White round, flat beveled edged uncoated tablets with breack line on one side. Shelf-life: Shelf-life is 3 years. Storage: Keep it out of reach of children, in a dry, dark place at temperature below 25 °C. Package: 4 tablet in blister. 1 blister in a carton box. Conditions of supply: By prescription.[/toggle]
[toggle title=”What special dietary instructions should I follow?” state=”close”]Unless your doctor tells you otherwise, continue your normal diet.[/toggle]
[toggle title=”What should I do if I forget a dose?” state=”close”]Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.[/toggle]
[toggle title=”What side effects can this medication cause?” state=”close”]Fluconazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: headache dizziness diarrhea stomach pain heartburn change in ability to taste food[/toggle]
[toggle title=”What should I know about storage and disposal of this medication?” state=”close”]Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Dispose of any unused liquid medication after 14 days. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. [/toggle]
[toggle title=”FREQUENTLY ASKED QUESTIONS FOR FLUCONAZOLE” state=”close”]
Question. What is Fluconazole used for?
Answer: Fluconazole is an antifungal medicine. It is used for the treatment of many fungal infections like Cryptococcal meningitis (fungal infection in the brain) and Coccidioidomycosis (a disease of the lungs).
Additionally, it is helpful in the treatment of infections caused by Candida found in the bloodstream, body organs (e.g., heart, lungs) or urinary tract, mucosal thrush (infection affecting the lining of the mouth, throat, and denture sore mouth), and genital thrush (infection of the vagina or penis). It can also be used to treat skin infections like athlete’s foot, ringworm, jock itch, and nail infection.
Question. Can Fluconazole be taken with oral contraceptives (OCPs) or birth control pills?
Answer: Fluconazole has been reported to have a minor interaction when taken with estradiol (a component of oral contraceptives). It can increase the level or effect of estradiol when given along with it. Before starting the treatment with Fluconazole inform your doctor if you are taking birth control pills. Q. Can Fluconazole cause hair loss? Fluconazole may cause hair loss as a rare side effect. If during the treatment you experience hair loss, inform your doctor.
Question. Is Fluconazole effective?
Answer: Yes, Fluconazole is effective when used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Fluconazole too early, the symptoms may return or worsen.
Question. Is Fluconazole fungistatic or fungicidal?
Answer: Fluconazole is primarily fungistatic which means it controls the growth of fungus). However, it may also act as a fungicidal (kills fungus) medicine against certain organisms, specifically Cryptococcus in a dose-dependent manner, specifically Cryptococcus.
Question. Does Fluconazole treat urinary tract infection (UTI)?
Answer: Fluconazole is used to treat urinary tract infections (UTI) caused mainly by Candida. However, bacteria growth can also cause UTI in some cases. If you are suffering from UTI, please consult your doctor as the cause of infection (fungal or bacterial, or other) needs to be identified before the start of any treatment.
Question. Can I take Fluconazole with alcohol?
Answer: Yes, Fluconazole can be taken with alcohol. No interactions have been reported between the two. However, it is better to consult your doctor on the use of alcohol before taking Fluconazole to avoid any side effects and get the maximum benefit of Fluconazole.
Question. What if I forget to take a dose of Fluconazole?
Answer: If you have missed a dose of Fluconazole, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Question. Can I take Fluconazole for yeast infection?
Answer: Yes, Fluconazole can be used for the treatment of yeast (candidal) infection. However, if you think you are suffering from a yeast infection, consult your doctor. This is because proper diagnosis is required before starting any therapy.
Question. Is Fluconazole a steroid?
Answer: No, Fluconazole is not a steroid. Fluconazole belongs to a group of medicines called antifungals.
Question. Does Fluconazole treat bacterial vaginosis?
Answer: No, Fluconazole does not treat bacterial vaginosis as it is not active against any bacteria. Fluconazole is used to treat infection of the vagina caused by Candida (a fungal infection). If you think you are suffering from bacterial vaginosis, consult your doctor. This is because the diagnosis of your infection (whether it is fungal or bacterial) is required to start your treatment.
Question. Does Fluconazole make you feel tired?
Answer: Yes, Fluconazole can make you feel tired. If you experience excessive tiredness during the treatment with this medicine, consult your doctor. The reason for tiredness could be a sign of an underlying liver problem as Fluconazole can affect your liver.
Question. Is Fluconazole over the counter (OTC)?
Answer: No, Fluconazole is not an over-the-counter (OTC) product. It is available only when prescribed by your doctor.
Question. Is Fluconazole safe to be used in pregnancy?
Answer: No, Fluconazole is not safe to be used in pregnancy. Studies suggest that the use of Fluconazole during pregnancy is harmful to the development of the baby. Therefore, Fluconazole is prescribed in pregnant women only if the benefits of the medicine outweigh the risks involved. However, if a woman gets pregnant during the treatment with Fluconazole, she must be well informed about the potential harm to the baby. If you are planning to conceive, are pregnant, or are breastfeeding, inform your doctor before taking Fluconazole.
Question.I feel better now, can I stop taking Fluconazole?
Answer: No, you should not stop taking Fluconazole suddenly without consulting your doctor. This is because suddenly stopping the medication may worsen your condition and your infection may return. Continue your medication even if you feel better as your symptoms may improve before the infection is completely cleared. Stopping the medication too early could allow the fungus to continue to grow and hence, prevent complete healing.[/toggle]
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview of the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, or replace or be a substitute for a registered medical practitioner’s medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site.
References:
https://www.medicines.org.uk/emc/product/4439/pil#gref
https://my.clevelandclinic.org/health/drugs/19527-fluconazole-tablets
https://www.drugs.com/mtm/fluconazole.html
https://medlineplus.gov/druginfo/meds/a690002.html
https://www.medicalnewstoday.com/articles/fluconazole-oral-tablet#dosage
