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Procedure For Handling of Market Complaints

Posted on February 11, 2021February 11, 2023 By ABHA
STANDARD OPERATING PROCEDURE
Title:Procedure For Handling of Market Complaints

OBJECTIVE

To lay down the Procedure for Handling of Market Complaints.

SCOPE

This Procedure is applicable for handling of market complaints received from wholesaler, Distributor, Retailer, Customer, Physicians, Patients, field staff etc. at Pharmaceutical Company.

RESPONSIBILITY

It is a joint responsibility of Manager-Marketing and Manager-Quality Assurance in  coordination with Quality Assurance.

It is a joint responsibility of Country Manager/Company appointed Business agent in coordination with Quality Assurance (In-case of Export).

Executive – Quality Assurance.

ACCOUNTABILITY

Manager – Quality Assurance.

PROCEDURE

RECEIPT OF PRODUCT COMPLAINT

COMPLAINT MAY BE RECEIVED FROM

Wholesaler

Distributor

Retailer

Customer

Physicians

Patients

Regulatory agencies/National Health Authorities

COMPLAINTS MAY BE GENERALLY RECEIVED BY FIELD STAFF

Medical representative

Manager – Marketing

Company appointed Business agent (In-case of export).

  • Complaint may be in written or verbal. In-case of telephonic message, the receiver shall try to get the detailed information so as to facilitate the investigation.
  • Manager- Marketing / Company Appointed Business agent shall take all the efforts to get a complaint sample (if applicable).
  • Manager- Marketing / Company Appointed Business agent shall send a copy of correspondence received from the complainant along with the complaint sample to Site, Manager – Quality Assurance.
  • All such complaints shall be addressed to the Manager-Quality Assurance.
  • On receipt of the complaint the following additional information shall be obtained.
    • Defected Product Name, Batch No(s).
    • Nature of defect & details.
    • Any adverse health problem occurred from the use.
    • Name and complete address of the complainant.
    • Stock details of the particular batch (s) in distribution chain.
    • Specimen sample of defect sample.
  • On receipt of the above information Manager-Marketing and Country Manager/Company appointed Business agent (In-case of export) shall forward the details to Site Quality Assurance along with the specimen sample of the defect product and a copy of correspondence received from the complainant.

HANDLING OF PRODUCT COMPLAINT.

On receipt of product complaint, Quality Assurance shall enter the details in the Market Complaint Register.

QA shall assign a unique, sequential number for each quality complaint as below

XX / XXX / XXX-XX 

Last Three Digits of Sr. No. Running Calendar Year

Next Three Digits of Sr. No.

Initiator Department Code

Company Code

FOLLOWING INFORMATION SHALL BE ENTERED INTO THE MARKET COMPLAINT REGISTER.

  • No.
  • Date
  • Complaint No.
  • Name, Address and Telephone Number of the Complainant.
  • Product Brand Name/Generic Name.
  • Batch No.
  • Date of Mfg/Exp date.
  • Details and nature of the complaint.
  • Investigation details.
  • Investigation Report send to Marketing / Country Manager.
  • Done by
  • Verified by
  • Remarks

 

  • In-case the complaint relates to an adverse effect on health or might produce an adverse effect on health, pass the information immediately to G.M. Technical and action shall be initiated within 24-48hrs.
  • In such case initiate recall committee meeting and proceed as per SOP Procedure for product recall.
  • On receipt of product complaint (In case of export), Company Appointed business agent will inform the National health authority/competent authority of the country on the nature of complaint to the competent authority of the country. Further the company appointed business agent will be continually updating the further proceedings of the complaint like impact of complaint, critical findings of investigation, possible effected batch(s) adverse effect on health, etc. to the National Health Authority/Competent Authority of the Country.
  • In case complaint is regarding the product quality and efficacy, Head Quality Assurance shall carry out detailed investigation, check the control samples of the same batch and analyze the same. Necessary help from QC may be taken, in case if stability is under question.
  • Investigation shall be extended to other batches, which may be affected by the reason of complainant.
  • Batch Production and control Record and related documents shall be checked thoroughly by Manager – Quality Assurance and Manager-Production to check for any deviations or abnormalities reported or recorded during the manufacturing of the subjected batch.
  • Manager-Quality Assurance along with the assistance of the Manager –Quality Control and Manager-Production shall conduct a detailed investigation of the defect and cause of the complaint.

INVESTIGATION SHOULD CONSIST OF THE FOLLOWING

    • Inspection of the defect product.
    • Analysis of the defect product, if required.
    • Examination of the control sample.
    • Review of the analytical report and related document.
    • Review of the Batch Manufacturing and Packing Records.
    • Review of the other related documents.
  • The findings of investigation shall be assessed by Manager –Quality Control & Manager-Production.
  • Finally Manager-Quality Assurance shall evaluate the investigation findings and propose corrective action to avoid the re-occurrence of the complained defect.
  • Document the investigation findings .
  • Based on the investigation findings if product defect is discovered in a batch, consideration should be given to check other batches in order to determine whether they are also affected.
  • After the investigation, appropriate follow-up action shall be initiated including product recall if necessary based on the evaluation of the complaint by Head medical.
  • The corrective action plan and measures taken as a result of complaints shall be recorded and referenced to the corresponding batch records.
  • Review the complaint records annually for any indication of specific or recurrent problems that require attention and might justify the recall of marketed products.
  • Copy of investigation report shall be sent to Manager-Marketing & Company appointed Business agent (In-case of export) to give feed back to the complainant.
  • Send a copy of investigation report to the competent authority of the country (When exported), together with all related information on the corrective action followed, and affected related batches distributed to the country and action plan taken for future.
  • Based on the investigation conclusion instruct the distribution in-charge to initiate hold of further distribution of the said batch(s) or to recall the said batch(s) from the distribution chain and arrange for free replacement.
  • All the documents related to the market complaints shall be retained at least one year beyond the expiration date of the product or one year after the, date of receipt of the complaint whichever is longer.
  • Closing time required for domestic market complaints is one month and for export market complaints, it is three months.

ABBREVIATIONS

SOP       –   Standard Operating Procedure

QA        –    Quality Assurance

ATTACHMENTS

Sr. No.Title  Format No.
7.1Product Complaint Form
7.2Market Complaint Investigation form
7.3Market Complaint Register

DISTRIBUTION LIST

Sr. No.Copy No.Department
Quality Assurance
Quality Control
Quality Control – Microbiology
Production
Engineering & Utility
Personnel & Administration
Warehouse

 

ATTACHMENT-I

PRODUCT COMPLAINT FORM

Complaint No.: …………………….

Date:                ..……………………..

To,

Manager  – Quality Assurance

1.0       Product           :            …………………………………………………………..

2.0       Batch No.        :            …………………………………………………………..

3.0       Date of Mfg.    :            …………………………………………………………..

4.0       Date of Exp.    :            …………………………………………………………..

5.0       Complaint received from

Party  ‚      Retailer ‚            Physician  ‚             Patient ‚                Others ‚

Regulatory agency/National Health authority /competent authority of Country  ‚

Address and phone number of the complainer.

……………………………………………………………………………………………………

……………………………………………………………………………………………………

6.0       Defected sample enclosed                            Yes (     )        No (     )

Nature of complaint

……………………………………………………………………………………………………

7.0       Defect related to adverse health problem      Yes (     )        No (     )

Details:

……………………………………………………………………………………………………

8.0       Complaint received by:

Sign & Date ______________________

(Marketing Department)

  • Defected sample received by

Sign & Date ______________________

(Marketing-Department)

10.0      Product complaint forwarded by

Sign ______________________

Date______________________

(Manager-Marketing)

 

ATTACHMENT-II

MARKET COMPLAINT INVESTIGATION FORM

Complaint No.                         :            ………………………………………………….

Complaint received on           :            ………………………………………………….

  • Defect sample inspection 
OKNot OKRemarks
a)Physical Appearance
b)Packaging Components
c)Printed Matter
d)Other if any (specify)

 2.0       Control Sample Evaluation:

OKNot OKRemarks
a)Physical appearance
b)Packaging Components
c)Printed Matter
d)Other if any (specify)

3.0       Analytical Evaluation:

(Q.C. Reports to be attached)

OKNot OKRemarks
a)Specimen Sample (Defected Product)
b)Control Sample
c)Review of analytical reports
d)Other related documents (Specify)

4.0       Batch document evaluation:

OKNot OKRemarks
a)Review of BMR/BPR
b)Other related documents (Specify)

 5.0       Product Details 

  • Product on which complaint received :

……………………………………………………………………………………………

  • Other related B. No, investigated

……………………………………………………………………………………………                              

6.0       Assessment of Complaint   

6.1       Review comments from Manager-Quality Control:

……………………………………………………………………………………………

Sign/Date: …………………………………………….

    (Manager-Quality Control)

6.2       Review comments from Manager- Production:

……………………………………………………………………………………………

Sign/Date: ………………………………………

(Manager-Production)

 7.0       Recommendations from Manager-Packing:

……………………………………………………………………………………………

Sign/Date: ……………………………………….

(Manager-Packing)

  • Comment on adverse effect on health (If applicable)

……………………………………………………………………………………………

Sign/Date: ………………………………………

(Head-Medical Officer) 

  • QA Evaluation of complaint :

……………………………………………………………………………………………

  • Details of Destruction (if Applicable):
Batch NoQuantityQuantity received from recalled/in stock/ Other than factoryMode of destruction

11.0      Action plan for the said batch(s):

11.1      To recall from market

11.2      To hold further distribution

11.3      To replace quantity

11.4      Others

Specify: ……………………………………………………………………………………………

12.0      Proposed Corrective Action for future:

……………………………………………………………………………………………

13.0 Conclusion Report:    

……………………………………………………………………………………………

Sign with Date:     ………………………….

(Manager – Quality Assurance)

  ATTACHMENT-III

MARKET COMPLAINT LOG

Sr. No.DateComplaint          No.Name, Address & Telephone No.Product NameBatch No.Mfg./Exp. DateDetails & Nature of ComplaintInvestigation

Details

Investigation report send to marketing onDone   byVerified byRemarks

 

 

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Bliss GVS Pharma Ltd-Vacancies for M.Pharm, B.Pharm, MSc in QA, QC, Production Apply

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Zydus Lifesciences -Walk In Interview on 19th March 2025

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Indeed Jobs-Symed Labs Ltd (Viyash Life Sciences) – Walk-In Drive for Quality Control / Quality Assurance / EHS / ETP on 17th-21st Dec’ 2024

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